[Effect of Staphylococcal proteinase on adherence of Candida albicans to mucous membrane cells in vitro].

The study was aimed at evaluation of influence of staphylococcal proteinase on adherence of Candida albicans to the cheek mucous membrane cells. Epithelial cells were preincubated with the enzyme which was followed by adherence tests. Significant increase of number of cells of Candida albicans adhering to epithelial cells preincubated with enzyme in concentrations of 10 micrograms/ml and 50 micrograms/ml, was detected. Staphylococcal serine protease seems to play an important role in mixed infections caused by fungi and bacteria.