[Comparative in vitro susceptibility of clinical bacterial isolates to pefloxacin and 14 antibiotics].

In vitro activity of pefloxacin against 782 bacterial strains isolated from hospitalized patients (July-September 1991) in Wrocław was compared with that of 14 antibiotics (4 aminoglycosides and 10 beta-lactamase). The most susceptible to pefloxacin were: Staphylococcus epidermidis (96.0%), Klebsiella (94.4%), Proteus mirabilis (93.8%) and Escherichia coli (92.7%). The least susceptible proved to be: nonfermentative Gram-negative rods (46.5%), and among them Pseudomonas aeruginosa (19.3% weakly sensitive, 0% sensitive strains). It was found that over 80% of Gram-negative rods were susceptible to pefloxacin, amikacin, netilmicin, cefotaxime and ceftriaxone. The most active against staphylococci were netilmicin (92.6%), pefloxacin (89.4%) and amikacin (82.5%).