Nilsdotter A-K, Petersson I F, Roos E M, Lohmander L S
Department of Orthopaedics, Lund University Hospital, Spenshult Hospital of Rheumatic Diseases, Halmstad, Sweden.
Ann Rheum Dis. 2003 Oct;62(10):923-30. doi: 10.1136/ard.62.10.923.
To investigate prospectively long term patient relevant outcomes after unilateral total hip replacement (THR) for osteoarthritis (OA). To identify non-responders to this intervention and patient related predictors of unsatisfactory outcome.
A case-control study comparing health related quality of life of 219 patients (mean age 71) after THR with that of a matched reference group of 117 subjects without hip complaints recruited from the community. Patients and reference group answered SF-36 and WOMAC questionnaires preoperatively, at 3, 6, 12 months, and at 3.6 years (range 26-65 months) postoperatively. Supplementary questions were asked at the final follow up.
198/211 (94%) of the patients and 83/109 (76%) of the reference group participated at the final follow up. At follow up, the only difference between the two groups in the SF-36 was physical function, where patients scored worse. Patients also reported worse WOMAC function. 31% of the patients had improved by <10/100 WOMAC score points for pain and/or function at final follow up, compared with preoperatively. More pain preoperatively and higher age and postoperative low back pain predicted a worse outcome in WOMAC function.
3.6 years after THR for OA, health related quality of life was similar for patients and reference group except for function, where patients had worse function. Higher age and more pain preoperatively predicted a poor outcome. Patients with hip OA with musculoskeletal comorbidities, such as low back pain and OA of the non-operated hip, have less long term functional improvement after THR.
前瞻性调查骨关节炎(OA)单侧全髋关节置换术(THR)后与患者相关的长期预后。识别对该干预无反应者以及预后不满意的患者相关预测因素。
一项病例对照研究,比较219例患者(平均年龄71岁)THR术后与从社区招募的117名无髋关节疾病匹配参照组的健康相关生活质量。患者和参照组在术前、术后3个月、6个月、12个月以及3.6年(范围26 - 65个月)回答SF - 36和WOMAC问卷。在最后一次随访时询问补充问题。
211例患者中的198例(94%)和参照组109例中的83例(76%)参与了最后一次随访。随访时,两组在SF - 36上的唯一差异在于身体功能,患者得分更低。患者还报告WOMAC功能更差。与术前相比,31%的患者在最后一次随访时疼痛和/或功能的WOMAC评分改善<10/100分。术前疼痛更严重、年龄更大以及术后腰痛预示WOMAC功能预后更差。
OA行THR术后3.6年,患者与参照组的健康相关生活质量在功能方面除外相似,患者功能更差。年龄更大和术前疼痛更严重预示预后不良。合并肌肉骨骼疾病如腰痛和未手术髋关节OA的髋关节OA患者THR术后长期功能改善较少。