Zuskin E, Mustajbegović J, Kanceljak B, Kern J
Skola narodnog zdravlja Andrija Stampar Medicinskog Fakulteta Sveucilista, Zagreb, Hrvatska.
Arh Hig Rada Toksikol. 1992 Dec;43(4):339-47.
The prevalence of acute and chronic respiratory symptoms and ventilatory capacity was studied in 50 textile workers exposed to sisal dust. A follow-up study was performed 19 years later and included 20 workers out of the 50. The first study showed a considerably higher prevalence of all chronic respiratory symptoms in the exposed than in control workers although the difference was statistically significant only for chest tightness (P < 0.01). Comparison of the prevalence in the first and the follow-up study in 20 textile workers revealed a statistically significant increase in the rate of chronic cough, dyspnea, chest tightness and nasal catarrh. During the follow-up study the prevalence of almost all chronic respiratory symptoms was significantly higher in exposed than in control workers. Results of ventilatory capacity in 50 sisal workers showed acute reductions of FVC and FEV1 during work shift on Monday and the following Thursday. Comparison of the measured and predicted normal values demonstrated lower values in the follow-up study in comparison to those in the first study. The mean annual fall of ventilatory capacity tests was 0.027 L for FVC and 0.036 L for FEV1. Data suggest that long-term exposure to sisal dust may cause the development of chronic respiratory symptoms and lung function impairment in sensitive subjects.
对50名接触剑麻粉尘的纺织工人的急性和慢性呼吸道症状及通气能力进行了研究。19年后进行了一项随访研究,50名工人中有20名参与。第一项研究表明,与对照工人相比,接触组所有慢性呼吸道症状的患病率显著更高,尽管差异仅在胸部发紧方面具有统计学意义(P < 0.01)。对20名纺织工人的第一项研究和随访研究中的患病率进行比较,发现慢性咳嗽、呼吸困难、胸部发紧和鼻粘膜炎的发生率有统计学意义的增加。在随访研究期间,几乎所有慢性呼吸道症状的患病率在接触组中显著高于对照工人。50名剑麻工人的通气能力结果显示,周一和接下来的周四工作班次期间,用力肺活量(FVC)和第一秒用力呼气容积(FEV1)急性下降。测量值与预测正常值的比较表明,随访研究中的值低于第一项研究中的值。FVC的通气能力测试平均每年下降0.027升,FEV1为0.036升。数据表明,长期接触剑麻粉尘可能会导致敏感个体出现慢性呼吸道症状和肺功能损害。