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瞬目后角膜前泪膜引流的建模

Modelling drainage of the precorneal tear film after a blink.

作者信息

Braun R J, Fitt A D

机构信息

Faculty of Mathematical Studies, University of Southampton, Southampton SO17 1BJ, UK.

出版信息

Math Med Biol. 2003 Mar;20(1):1-28. doi: 10.1093/imammb/20.1.1.

Abstract

We study the drainage of the precorneal tear film in humans. A fluid dynamic model for the drainage of the aqueous layer is developed that includes the effects of evaporation and gravity. The model may be reduced to a single nonlinear partial differential equation for the thickness of the aqueous layer. The equation is solved numerically and accurate times for film rupture are obtained for physically realistic parameters. The results indicate that although gravity and evaporation are not the most dominant effects in some parts of the film, they can nevertheless materially affect the film drainage process and should therefore be included in models for tear film drainage.

摘要

我们研究了人类角膜前泪膜的排出情况。建立了一个用于水液层排出的流体动力学模型,该模型考虑了蒸发和重力的影响。该模型可简化为一个关于水液层厚度的非线性偏微分方程。通过数值求解该方程,针对符合实际物理参数的情况,得到了泪膜破裂的准确时间。结果表明,尽管在泪膜的某些部分重力和蒸发并非最主要的影响因素,但它们仍能对泪膜排出过程产生实质性影响,因此在泪膜排出模型中应予以考虑。

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