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[15岁以下儿童水痘并发症的住院情况]

[Hospital admissions for varicella complications in children aged less than 15 years old].

作者信息

Pérez-Yarza E-G, Arranz L, Alustiza J, Azkunaga B, Uriz J, Sarasua A, Mendiburu I, Emparanza J I

机构信息

Servicio de Pediatría, Hospital Donostia, San Sebastián, España.

出版信息

An Pediatr (Barc). 2003 Sep;59(3):229-33. doi: 10.1016/s1695-4033(03)78170-3.

Abstract

BACKGROUND

The complications of varicella are one of the arguments in favor of universal vaccination programs in children.

OBJECTIVE

To describe the complications of varicella requiring hospital admission in a well-defined population (Gipuzkoa, Spain) and to compare the incidence of hospitalization with that reported in other series.

MATERIAL AND METHODS

Observational, retrospective, multicenter study of admissions for varicella. The medical histories codified as varicella (minimum data set, CIE-0, codes 952.0-052.9) from 1 January 1993 to 31 December 2002 were reviewed. Calculation of hospitalization rates was based on emergency department visits and population data. The pediatric population of Gipuzkoa seeking medical attention at one of the four Basque Country Health Service hospitals in the area: Hondarribia, Mendaro, San Sebastian and Zumarraga. The mean coverage in Gipuzkoa is 54,999 children aged less than 15 years/year. All the children aged 0-15 years old admitted for more than 24 h with a discharge diagnosis of varicella complications. The variables studied are: age, gender, personal history, varicella immunization, immune status, fever, chest X-ray, complementary investigations, length of hospital stay, treatment, discharge diagnosis, clinical course, complications and sequelae at discharge.

RESULTS

Seventy-one children were hospitalized. None had been vaccinated against the varicella-zoster virus. Eighty percent were aged less than 5 years and three were immunocompromised. Fifty-six percent had bacterial superinfection and invasive forms were found in seven patients. The mean length of admission was 6.5 days +/- 5.1. No deaths or sequelae were reported.

CONCLUSIONS

The annual incidence rate of admissions longer than 24 hours due to varicella complications was 12.9 cases per 100,000 children aged less than 15 years, representing 0.31% of all annual admissions in this age group.

摘要

背景

水痘并发症是支持儿童普遍接种疫苗计划的论据之一。

目的

描述在一个明确界定的人群(西班牙吉普斯夸省)中因水痘需住院治疗的并发症,并将住院率与其他系列报道的进行比较。

材料与方法

对水痘住院病例进行观察性、回顾性、多中心研究。回顾了1993年1月1日至2002年12月31日编码为水痘(最小数据集,国际疾病分类-0,编码952.0 - 052.9)的病史。住院率的计算基于急诊科就诊情况和人口数据。研究对象为在该地区巴斯克地区四家卫生服务医院(洪达里比亚、门达罗、圣塞瓦斯蒂安和苏马拉加)之一寻求医疗服务的吉普斯夸省儿科人群。吉普斯夸省的平均覆盖人群为每年54,999名15岁以下儿童。所有0 - 15岁因水痘并发症住院超过24小时且出院诊断为此病的儿童。研究变量包括:年龄、性别、个人病史、水痘免疫接种情况、免疫状态、发热、胸部X线检查、辅助检查、住院时间、治疗、出院诊断、临床病程、并发症及出院时的后遗症。

结果

71名儿童住院。无人接种过水痘 - 带状疱疹病毒疫苗。80%年龄小于5岁,3名免疫功能低下。56%发生细菌重叠感染,7名患者出现侵袭性感染形式。平均住院时间为6.5天±5.1天。无死亡或后遗症报告。

结论

因水痘并发症导致住院超过24小时的年发病率为每100,000名15岁以下儿童中有12.9例,占该年龄组所有年度住院病例的0.31%。

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