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[Lethal effect of boron neutron capture reaction on human uveal melanoma cells in culture incubated with borophenylalanine].

作者信息

Belkhou R, Mykita S, Meyer L, Sahel J, Abbé J C, Dreyfus H, Massarelli R

机构信息

Centre de Recherches nucléaires, Strasbourg.

出版信息

C R Acad Sci III. 1992;315(12):485-91.

PMID:1297526
Abstract

Cell cultures obtained from human uveal tumours have been used as experimental model to study the lethal effect consecutive to the neutron capture reaction on boron incorporated into cells as borophenylalanine. An irradiation with a neutron fluence of 6 x 10(9) n cm-2 reduced the number of viable cells by about 30%.

摘要

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引用本文的文献

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Uptake and metabolism of boronophenylalanine in human uveal melanoma cells in culture Relevance to boron neutron capture therapy of cancer cells.硼苯丙氨酸在人眼葡萄膜黑色素瘤细胞中的摄取和代谢与癌细胞硼中子俘获治疗的相关性。
Amino Acids. 1995 Jun;8(2):217-29. doi: 10.1007/BF00806495.