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[慢性胃病脾气虚证与肝郁气滞证和胃电图、胃黏膜病理及脉象 - 心血管功能的关系]

[Relation among syndrome of spleen deficiency and stagnation of liver-qi and electrogastrogram, gastric mucosal pathology and pulse-cardiovascular function in chronic gastric diseases].

作者信息

Zou X G, Lin Q, Zhuang Z C

机构信息

Fujian Institute of TCM, Fuzhou.

出版信息

Zhongguo Zhong Xi Yi Jie He Za Zhi. 1992 Sep;12(9):519-20, 515.

PMID:1298464
Abstract

In this research, Syndrome of Deficiency of Spleen (DS) and Stagnation of Liver-Qi (SLQ) as well as observations of electrogastrogram (EGG), gastric mucosal pathology and pulse cardiovascular examination were investigated in 56 cases of chronic gastric diseases (CGD). The results showed: (1) In SLQ with DS the amplitude of EGG was significantly higher than that of the control group (P < 0.01), it often indicated the active period of pathologic change, but in DS with SLQ, the amplitude of EGG was significantly lower than that of the control group (P < 0.01), it frequently denoted the static period. In case that DS equalled to SLQ, the amplitude of EGG was significantly higher than that of the control group (P < 0.01). It revealed that there were no significant difference between the patient's number of static and active periods (P > 0.05). It is valuable in Syndrome Differentiation of Deficiency and Excess and analysis of Superficiality and Origin in CGD. (2) Cardiovascular function was also affected in Syndrome differentiation of DS and SLQ. DS with SLQ manifested itself as reduction of left ventricle pump and declination for metabolism of microcirculation, they had significant difference as compared with the control group (P < 0.05), while SLQ with DS or equality between DS and SLQ had the normal function of left ventricle pump and metabolism of microcirculation, even though cardiac output were higher than that of control group (P < 0.05). It showed that the traditional Chinese medicine theory of interrelation among Heart and Spleen, Liver had their own hemodynamic bases.

摘要

本研究对56例慢性胃病患者进行了脾虚证、肝郁证以及胃电图(EGG)、胃黏膜病理和脉象心血管检查。结果显示:(1)肝郁脾虚组EGG波幅显著高于对照组(P<0.01),常提示病变活动期;而脾虚肝郁组EGG波幅显著低于对照组(P<0.01),常提示病变静止期。脾虚肝郁程度相等时,EGG波幅显著高于对照组(P<0.01)。静止期与活动期患者数量无显著差异(P>0.05)。这对慢性胃病的虚实辨证及表里分析具有重要价值。(2)脾虚证与肝郁证的辨证中,心血管功能也受到影响。脾虚肝郁表现为左心室泵血功能降低及微循环代谢下降,与对照组相比有显著差异(P<0.05);而肝郁脾虚或脾虚肝郁程度相等时,左心室泵血及微循环代谢功能正常,心输出量虽高于对照组(P<0.05)。这表明中医心脾、肝相关理论有其自身的血液动力学基础。

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