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[实验性脾虚大鼠的胃电活动和胃动力]

[Gastroelectric activity and gastric motility in experimental spleen deficiency rats].

作者信息

Qu R Y, Wang X Q, Yang J

机构信息

Capital College of Medicine, Beijing.

出版信息

Zhongguo Zhong Xi Yi Jie He Za Zhi. 1994 Mar;14(3):156-8, 133-4.

PMID:7950186
Abstract

Using electrode and highly sensitive strain sensor to record alterations of gastroelectric activity and gastric motility, during experimental Spleen Deficiency (SD) rats was conducted. As compared with control, frequency of slow wave (time/3 min) did not obviously change (11.71 +/- 0.71 and 12.50 +/- 0.55, P < 0.05), but amplitude (mV) of which reduced significantly (0.14 +/- 0.05 and 0.37 +/- 0.04, P < 0.01), while that of fast wave also decreased. In self-recovered group, the amplitude of slow wave recovered slightly (0.22 +/- 0.08 and 0.37 +/- 0.04, P > 0.005). After treatment with modified Sijunzi Tang ([symbol: see text]), the gastric activities of SD rats elevated to levels of control (P > 0.05), but gastric motility remained weak in SD group. Although the motility of self-recovered group improved to a certain degree, however, the main indices had no significant difference from SD group (P > 0.05). It suggested that there were significant changes of gastric activity in SD and Chinese herbs could improve the syndrome apparently.

摘要

采用电极和高灵敏度应变传感器记录实验性脾虚大鼠胃电活动和胃动力的变化。与对照组相比,慢波频率(次/3分钟)无明显变化(11.71±0.71和12.50±0.55,P<0.05),但其振幅(mV)显著降低(0.14±0.05和0.37±0.04,P<0.01),快波振幅也降低。自愈组慢波振幅略有恢复(0.22±0.08和0.37±0.04,P>0.005)。用加味四君子汤治疗后,脾虚大鼠的胃活动升高至对照组水平(P>0.05),但脾虚组胃动力仍较弱。自愈组的动力虽有一定程度改善,但主要指标与脾虚组无显著差异(P>0.05)。提示脾虚大鼠胃活动有显著变化,中药能明显改善该证候。

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