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[苯乙烯暴露工人外周血细胞遗传学损伤的研究]

[Study of cytogenetic damages in peripheral blood of styrene exposed workers].

作者信息

Huang M

机构信息

Beijing Institute of labour hygiene and occupational diseases.

出版信息

Zhonghua Yu Fang Yi Xue Za Zhi. 1992 Sep;26(5):272-4.

PMID:1298602
Abstract

The three indices of chromosome aberration (CA), sister-chromatid exchanges (SCEs) and micronuclei were used simultaneously to ascertain the cytogenetic effects on eighty-three styrene exposed workers under current industrial hygienic conditions in two glass fiber reinforced plastics factories. Our results showed that exposure to styrene at a concentration of 129.3 mg/m3 (range 48.3-223.9 mg/m3) could result in an increase of the frequencies of CA and micronuclei but had little influence on the frequency of SCEs.

摘要

同时使用染色体畸变(CA)、姐妹染色单体交换(SCEs)和微核这三个指标,来确定在两家玻璃纤维增强塑料厂当前工业卫生条件下,83名接触苯乙烯的工人的细胞遗传学效应。我们的结果表明,暴露于浓度为129.3毫克/立方米(范围48.3 - 223.9毫克/立方米)的苯乙烯中,可能会导致CA和微核频率增加,但对SCEs频率影响不大。

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