Cook S D, Baffes G C, Wolfe M W, Palafox A J
Department of Orthopaedic Surgery, Tulane University School of Medicine, New Orleans, LA 70112.
J Oral Implantol. 1992;18(4):359-65.
The application of hydroxylapatite coatings promises marked improvement in the rapidity and durability of osseointegration for both dental and orthopedic metallic implants. Standard methods for the in vivo assessment of the performance of experimental implants include canine mandibular and femoral transcortical implantations. This study compared the results of the two procedures by use of similar HA-coated titanium implants. The results indicate that the rapidity of osseointegration and the maximum attachment strength for mandibular dental implants approximate those of the femoral transcortical implants, especially at longer post-operative intervals. We conclude that the two models are comparable for the purpose of evaluating the performance of this type of implant and can be used interchangeably by dental and orthopedic implant designers. HA-coating of titanium implants provides extensive osseointegration in both mandibular and long-bone models, with similar mechanical attachment strengths and histologic appearance.
羟基磷灰石涂层的应用有望显著提高牙科和整形外科金属植入物骨整合的速度和耐久性。体内评估实验性植入物性能的标准方法包括犬下颌骨和股骨皮质穿通植入术。本研究通过使用类似的羟基磷灰石涂层钛植入物比较了这两种手术的结果。结果表明，下颌牙种植体的骨整合速度和最大附着强度与股骨皮质穿通植入物相近，尤其是在术后较长时间间隔时。我们得出结论，为评估这类植入物的性能，这两种模型具有可比性，牙科和整形外科植入物设计者可互换使用。钛植入物的羟基磷灰石涂层在颌骨和长骨模型中均能实现广泛的骨整合，且具有相似的机械附着强度和组织学外观。
