Cook S D, Rust-Dawicki A M
Department of Orthopaedic Surgery, Tulane University, School of Medicine, New Orleans, Louisiana 70112, USA.
J Oral Implantol. 1995;21(3):191-200.
The histology of a CSTi (cancellous-structured titanium) porous-coated cylindrical dental implant was compared with that of a solid control HA (hydroxylapatite)-coated dental implant with the same geometry. A particular concern with the use of porous-coated implants in dental applications is the possibility of infection due to direct exposure to the outside environment. Three implants of each type were placed in healed mandibular sites of 14 canines, and after eight weeks of healing, an abutment was placed on each implant. In one half of the implants, ligature-induced peri-implantitis was introduced. The implants were evaluated at four, eight, 16, and 26 weeks post-ligature placement. Bone ingrowth percentages were relatively high for both ligated and non-ligated CSTi specimens, with mean values ranging from 59% to 71%. There was no significant difference in bone ingrowth percentages between ligated and non-ligated specimens at any of the evaluation periods. For the HA-coated specimens, there was also no significant difference in bone contact percentages between ligated and non-ligated implants. There was not a significant decrease in bone contact of bone ingrowth with time for either the ligated or non-ligated implants. No loss of bone along the porous coating or coating-bone interface was observed due to the peri-implantitis, although HA failure was seen primarily in ligated specimens. When crestal bone loss was evaluated on histologic sections and radiographs, it was found that there was no significant difference in loss between CSTi- and HA-coated implants at all time periods for ligated and non-ligated specimens. Histological inspection of the CSTi implants did not reveal any migration of infection or inflammation through the porous coating resulting in bone ingrowth loss.
将具有松质结构的钛（CSTi）多孔涂层圆柱形牙科植入物的组织学与具有相同几何形状的固体对照羟基磷灰石（HA）涂层牙科植入物的组织学进行了比较。在牙科应用中使用多孔涂层植入物的一个特别关注点是由于直接暴露于外部环境而导致感染的可能性。将每种类型的三个植入物放置在14只犬的愈合下颌部位，愈合八周后，在每个植入物上放置一个基台。在一半的植入物中，引入了结扎诱导的种植体周围炎。在结扎放置后的4周、8周、16周和26周对植入物进行评估。结扎和未结扎的CSTi标本的骨长入百分比相对较高，平均值在59%至71%之间。在任何评估期，结扎和未结扎标本之间的骨长入百分比均无显著差异。对于HA涂层标本，结扎和未结扎植入物之间的骨接触百分比也无显著差异。结扎和未结扎植入物的骨接触或骨长入均未随时间显著减少。尽管主要在结扎标本中观察到HA失效，但未观察到由于种植体周围炎导致沿多孔涂层或涂层-骨界面的骨丢失。当在组织学切片和X线片上评估嵴顶骨丢失时发现，对于结扎和未结扎标本，在所有时间段，CSTi涂层和HA涂层植入物之间的骨丢失没有显著差异。对CSTi植入物的组织学检查未发现感染或炎症通过多孔涂层迁移导致骨长入丢失。
