Silverstein L H, Kraft J D, Wand R
J Oral Implantol. 1992;18(4):394-8.
The biologic principle of guided tissue regeneration (GTR) has been studied extensively in hopes of regenerating alveolar bone. Various materials have been utilized as regenerative membranes; however, all materials have disadvantages, and the ideal membrane material is yet to be identified. In this case report, human freeze-dried fascia lata strips were used as a regenerative barrier membrane in conjunction with the placement of endosseous root implants and demineralized, freeze-dried bone allograft. The major advantage in the use of human fascia lata for guided tissue regeneration is that a second procedure to remove the material is not necessary, and the fascia is accepted by the surrounding tissues without complication. There is acceptance of four endosseous root-form dental implants that were immediately placed into fresh extraction sockets and covered with demineralized freeze-dried bone allograft (DFDBA), with human freeze-dried fascia lata used to serve as a biocompatible, collagenous, regenerative augmentation membrane over the dental implants. The biologic concept of GTR is clinically applied to increase the dimensions of the edentulous, maxillary alveolar ridge with use of human freeze-dried fascia lata barrier membranes.
引导组织再生（GTR）的生物学原理已得到广泛研究，以期实现牙槽骨再生。多种材料已被用作再生膜；然而，所有材料都存在缺点，理想的膜材料尚未确定。在本病例报告中，人冻干阔筋膜条被用作再生屏障膜，同时植入骨内牙根种植体并使用脱矿冻干同种异体骨。使用人阔筋膜进行引导组织再生的主要优点是无需二次手术取出材料，且筋膜能被周围组织接受而无并发症。四颗骨内根形牙种植体即刻植入新鲜拔牙窝，覆盖脱矿冻干同种异体骨（DFDBA），用人冻干阔筋膜作为种植体上的生物相容性胶原再生增强膜。GTR的生物学概念在临床上应用于通过使用人冻干阔筋膜屏障膜来增加无牙上颌牙槽嵴的尺寸。
