PhD, assistant professor.
PhD, full professor.
Braz J Otorhinolaryngol. 2011 Jul-Aug;77(4):439-446. doi: 10.1590/S1808-86942011000400006.
Few studies has been done using guided bone regeneration in maxillary sinus defects.
To assess the bone repair process in surgical defects on the alveolar wall of the monkey maxillary sinus, which communicates with the sinus cavity, by using collagen membranes: Gen-derm--Genius Baumer, Pro-tape--Proline and autologous temporal fascia.
In this prospective and experimental study, orosinusal communications were performed in four tufted capuchin monkeys (Cebus apella) and histologic analysis was carried out 180 days after.
In the defects without a cover (control), bone proliferation predominated in two animals and fibrous connective tissue predominated in the other two. In defects repaired with a temporal fascia flap, fibrous connective tissue predominated in three animals and bone proliferation predominated in one. In the defects repaired with Gen-derm or Pro-tape collagen membranes there was complete bone proliferation in three animals and fibrous connective tissue in one.
Surgical defect can be repaired with both bone tissue and fibrous connective tissue in all study groups; collagen membranes was more beneficial in the bone repair process than temporal fascia or absence of a barrier.
使用引导骨再生技术治疗上颌窦缺损的研究较少。
通过使用胶原膜(Gen-derm-Genius Baumer、Pro-tape-Proline 和自体颞筋膜)评估与窦腔相通的猴上颌窦牙槽骨壁手术缺损中的骨修复过程。
在这项前瞻性和实验性研究中,对四只卷尾猴(Cebus apella)进行了口鼻窦相通术,并在 180 天后进行了组织学分析。
在无覆盖物(对照)的缺损中,有 2 只动物的骨增生占主导地位,另外 2 只动物的纤维结缔组织占主导地位。在用颞筋膜瓣修复的缺损中,有 3 只动物的纤维结缔组织占主导地位,1 只动物的骨增生占主导地位。在用 Gen-derm 或 Pro-tape 胶原膜修复的缺损中,有 3 只动物完全骨增生,1 只动物纤维结缔组织增生。
在所有研究组中,手术缺损均可由骨组织和纤维结缔组织修复;胶原膜在骨修复过程中比颞筋膜或无屏障更有益。