Lyford Robert H, Mills Michael P, Knapp Charles I, Scheyer E Todd, Mellonig James T
Department of Periodontics, University of Texas Health Science Center at San Antonio, 78229-3900, USA.
Int J Periodontics Restorative Dent. 2003 Oct;23(5):417-25.
Various grafting materials have been used in guided bone regeneration procedures to augment alveolar ridges deficient in horizontal or vertical dimensions or both. Autogenous block grafts from intraoral and extraoral sites have been used for ridge augmentation with encouraging results. However, the risk of vascular and neurologic injury at the donor site as well as postoperative patient morbidity have been reported following these surgical procedures. The use of a cancellous block allograft could be one alternative to avoid potential donor site complications. Five deficient alveolar ridges in three patients were each grafted with a freeze-dried cancellous block allograft and a resorbable barrier membrane. Ridge measurements taken at baseline, graft placement, and a 6-month reentry surgery demonstrated an increase in alveolar ridge width from 2 to 4 mm. These gains in ridge width compare favorably with other guided bone regeneration studies, suggesting that a freeze-dried cancellous block allograft in conjunction with a resorbable membrane may be an acceptable alternative to the autogenous block graft in the treatment of compromised alveolar ridge deficiencies.
在引导骨再生手术中，已使用多种移植材料来增加水平或垂直尺寸不足或两者皆不足的牙槽嵴。来自口腔内和口腔外部位的自体块状移植已用于牙槽嵴增高，效果令人鼓舞。然而，这些手术术后已报道了供区血管和神经损伤的风险以及患者术后发病率。使用松质骨块状同种异体移植可能是避免潜在供区并发症的一种替代方法。三名患者的五条牙槽嵴缺损分别用冻干松质骨块状同种异体移植和可吸收屏障膜进行移植。在基线、移植植入时以及6个月再次手术时进行的牙槽嵴测量显示，牙槽嵴宽度从2毫米增加到4毫米。这些牙槽嵴宽度的增加与其他引导骨再生研究相比具有优势，表明冻干松质骨块状同种异体移植与可吸收膜联合使用可能是治疗受损牙槽嵴缺损时自体块状移植的一种可接受的替代方法。
