Gundel R E, Kaplan E N, Rosen J S
Contact Lens Research Group, State College of Optometry, State University of New York, New York.
Optom Vis Sci. 1992 Dec;69(12):948-52. doi: 10.1097/00006324-199212000-00007.
Discoloration of hydrogel contact lenses is frequently encountered in clinical practice and often precipitates lens replacement. This investigation sought to determine if lens discoloration was associated with a compromise in low or high contrast, high illumination visual acuity. This association would lead to a more scientific rationale for lens replacement. Amber lens discoloration was achieved using human-worn 55% water hydrophilic contact lenses (Methafilcon-A) heated in a 1% potassium sorbate, low pH saline solution. A spectrum of 6 discolored lenses was obtained with a peak absorbance at 320 nm. Fifteen subjects, between the ages of 22 and 38 years, were tested wearing each of the discolored lenses. None of the differences in high or low contrast acuity between our discolored and nondiscolored lenses were found to be statistically significant using a paired t-test at the 99% significance level.
水凝胶隐形眼镜变色在临床实践中经常遇到,并且常常促使更换镜片。本研究旨在确定镜片变色是否与低对比度或高对比度、高照度视力下降有关。这种关联将为更换镜片提供更科学的依据。使用在1%山梨酸钾、低pH值盐溶液中加热的55%含水量的亲水性隐形眼镜(Methafilcon - A)实现琥珀色镜片变色。获得了6个变色镜片的光谱,其在320nm处有最大吸光度。对15名年龄在22岁至38岁之间的受试者佩戴每个变色镜片进行了测试。在99%的显著性水平下,使用配对t检验发现,变色镜片和未变色镜片之间的高对比度或低对比度视力差异均无统计学意义。