Liozon F, Jauberteau-Marchan M O, Liozon E, Vidal E
Service de Médecine Interne A, CHRU Dupuytren, Limoges.
Ann Med Interne (Paris). 1992;143(7):433-7.
A prospective study on 11 patients with temporal artery biopsy-proven arteritis examined the frequency and significance of anti-cardiolipin antibodies. Antibody levels in 7 patients were higher than 20 units but were not correlated with an inflammatory syndrome, as assessed by measurement of 4 inflammatory proteins (fibrinogen, C-reactive protein, orosomucoid and haptoglobin). These 7 patients were treated with steroids and their antibody levels returned to the normal range after 4 to 16 weeks of therapy, later than the inflammatory proteins. Two patients had slight increases of their anti-cardiolipin antibody levels, but no signs of clinical relapse or increases of inflammatory proteins were observed. In this study, no correlation was found between the presence of anti-cardiolipin antibodies and the occurrence of ischemic complications in 6 of the 11 patients.
一项针对11例经颞动脉活检证实为动脉炎患者的前瞻性研究，检测了抗心磷脂抗体的频率及意义。7例患者的抗体水平高于20单位，但与炎症综合征无关，这是通过检测4种炎症蛋白（纤维蛋白原、C反应蛋白、类粘蛋白和触珠蛋白）来评估的。这7例患者接受了类固醇治疗，治疗4至16周后其抗体水平恢复到正常范围，比炎症蛋白恢复正常的时间晚。2例患者的抗心磷脂抗体水平略有升高，但未观察到临床复发迹象或炎症蛋白增加。在本研究中，11例患者中有6例抗心磷脂抗体的存在与缺血性并发症的发生之间未发现相关性。
