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[评估贲门失弛缓症患者食管功能的测压指标]

[Manometry indexes for evaluating esophageal function in patients with achalasia].

作者信息

Ge F

机构信息

Peking Union Medical College Hospital, Beijing.

出版信息

Zhonghua Wai Ke Za Zhi. 1992 Jul;30(7):394-6, 443.

PMID:1301338
Abstract

In 43 patients with achalasia (postoperative 18, post-dilatation 15, preoperative 10, and 10 normal people) esophageal manometry, esophageal emptying barium test and endoscopy were employed. The results showed that the esophageal emptying index EEI was 13.3 +/- 9.0 in the postoperative group, 4.7 +/- 7.6 in the post dilatation group, 50.0 +/- 17.4 in the normal group, 2.9 +/- 4.3 in the preoperative group. A linear relationship was seen between EEI and the lower esophageal barium retention area (So) (t = -5.00, P < 0.001). In patient with higher EEI and smaller So stronger esophageal emptying function was noted at swallowing. 80% of patients with less than 12 esophageal anti-reflux index (ARI) suffered from gastroesophageal reflux EEI and ARI can evaluate not only the esophageal motor functions but also the therapeutic effects of different treatment methods. The therapeutic effects are determined by esophageal peristalsis pressure and LES relaxation rate after LES is relaxed.

摘要

对43例贲门失弛缓症患者(术后18例、扩张后15例、术前10例)及10名正常人进行食管测压、食管排空钡餐试验和内镜检查。结果显示,术后组食管排空指数(EEI)为13.3±9.0,扩张后组为4.7±7.6,正常组为50.0±17.4,术前组为2.9±4.3。EEI与食管下段钡剂潴留面积(So)之间呈线性关系(t=-5.00,P<0.001)。EEI越高、So越小的患者,吞咽时食管排空功能越强。食管抗反流指数(ARI)小于12的患者中,80%患有胃食管反流。EEI和ARI不仅可以评估食管运动功能,还可以评估不同治疗方法的治疗效果。治疗效果由食管蠕动压力和LES松弛后LES的松弛率决定。

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