Sallet G, Kestelyn P
Department of Ophthalmology, University Hospital, Ghent, Belgium.
Bull Soc Belge Ophtalmol. 1992;243:99-107.
Radiation-induced optic neuropathy is a well-known complication of cranial radiotherapy. We describe four cases. In two cases, the diagnosis was made on MRI. After administration of Gadolinium-DTPA, there was an enhanced captation at the level of the optic nerve. In addition we reviewed 47 cases reported in the literature. Visual prognosis is less than 1/10 in 78% of affected eyes. In case of associated brain necrosis, the mortality rate is 62%.
放射性视神经病变是颅脑放疗一种众所周知的并发症。我们描述了4例病例。其中2例通过磁共振成像（MRI）做出诊断。给予钆喷酸葡胺后，视神经水平出现强化摄取。此外，我们回顾了文献报道的47例病例。78%的患眼视力预后低于1/10。若伴有脑坏死，死亡率为62%。
