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放射性视神经病变:磁共振成像与放射剂量测定的相关性

Radiation-induced optic neuropathy: correlation of MR imaging and radiation dosimetry.

作者信息

Young W C, Thornton A F, Gebarski S S, Cornblath W T

机构信息

Department of Radiology, University of Michigan Medical School, Ann Arbor.

出版信息

Radiology. 1992 Dec;185(3):904-7. doi: 10.1148/radiology.185.3.1438784.

Abstract

The authors performed topographic correlation of dosimetric measurements with contrast medium-enhanced magnetic resonance (MR) imaging signal aberration in two cases of radiation optic neuropathy. The region of pathologic contrast enhancement in the optic nerve and chiasm had received 55-62 Gy, which supports the theory that the risk of injury to the optic nerve and chiasm increases steeply with radiation doses above the tolerance level of 50-55 Gy.

摘要

作者对两例放射性视神经病变患者进行了剂量测定与造影剂增强磁共振(MR)成像信号异常的地形相关性研究。视神经和视交叉的病理性造影剂增强区域接受了55 - 62 Gy的辐射剂量,这支持了以下理论:当辐射剂量超过50 - 55 Gy的耐受水平时,视神经和视交叉受损的风险会急剧增加。

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