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质子束照射后迟发性视神经并发症

Delayed optic nerve complications after proton beam irradiation.

作者信息

Chacko Joseph G, Schatz Norman J, Glaser Joel S

机构信息

Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL, USA.

出版信息

Ann Ophthalmol (Skokie). 2008 Fall-Winter;40(3-4):166-70.

Abstract

We present two cases of delayed optic nerve complications following proton beam radiotherapy. Patient 1 received radiotherapy after surgery for clival chordoma and developed sequential radiation optic neuropathy at 5 and 9 months. Patient 2 developed optic nerve hemorrhage post radiotherapy for optic nerve sheath meningioma. These two cases of blindness demonstrate the risks associated with proton beam radiotherapy.

摘要

我们报告了两例质子束放射治疗后出现延迟性视神经并发症的病例。病例1在斜坡脊索瘤手术后接受放疗,分别在5个月和9个月时出现迟发性放射性视神经病变。病例2在视神经鞘膜瘤放疗后出现视神经出血。这两例失明病例表明了质子束放射治疗存在的风险。

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