Chacko Joseph G, Schatz Norman J, Glaser Joel S
Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL, USA.
Ann Ophthalmol (Skokie). 2008 Fall-Winter;40(3-4):166-70.
We present two cases of delayed optic nerve complications following proton beam radiotherapy. Patient 1 received radiotherapy after surgery for clival chordoma and developed sequential radiation optic neuropathy at 5 and 9 months. Patient 2 developed optic nerve hemorrhage post radiotherapy for optic nerve sheath meningioma. These two cases of blindness demonstrate the risks associated with proton beam radiotherapy.
我们报告了两例质子束放射治疗后出现延迟性视神经并发症的病例。病例1在斜坡脊索瘤手术后接受放疗,分别在5个月和9个月时出现迟发性放射性视神经病变。病例2在视神经鞘膜瘤放疗后出现视神经出血。这两例失明病例表明了质子束放射治疗存在的风险。