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孟加拉国人群中的恒河猴基因型频率。

Rhesus genotype frequency in Bangladeshi population.

作者信息

Rahman M, Abdulla A Z, Nandy C K, Mollah M A

机构信息

Department of Blood Trasnfusion, Institute of Postgraduate Medicine and Research, Dhaka.

出版信息

Bangladesh Med Res Counc Bull. 1992 Dec;18(2):89-94.

PMID:1303087
Abstract

The prevalence of Rhesus genotypes in Bangladesh has been studied and several important findings were observed. This being the initial report, includes a population of 1600 only. By using five Rh antisera (Anti-C, Anti-D, Anti-E, Anti-c and Anti-e) a genotype can be deduced since anti-d is not available. More often only a probable genotype can be suggested after reference to the known chromosome frequencies in the population. By using family studies in conjunction, it may be possible to determine genotype with certainty. The prominent Rhesus genotype was CDe/cDE (R1R2), i.e., 39.75%, Rhesus genotype cde/cde (rr) was found to be only 1.75%. The genotype cdE/cde (r"r) was not detected in the present series of Bangladeshi population. These results have been compared with the English and the Indian Bengalee Hindu Population.

摘要

孟加拉国恒河猴基因型的流行情况已得到研究,并观察到了一些重要发现。这是初始报告,仅涵盖1600人的群体。由于没有抗 - d血清,通过使用五种Rh抗血清(抗 - C、抗 - D、抗 - E、抗 - c和抗 - e)可以推断出基因型。更多时候,参考人群中已知的染色体频率后,只能提出可能的基因型。结合家系研究,有可能确定基因型。主要的恒河猴基因型是CDe/cDE(R1R2),即39.75%,恒河猴基因型cde/cde(rr)仅为1.75%。在本系列孟加拉国人群中未检测到基因型cdE/cde(r”r)。这些结果已与英国和印度孟加拉印度教人群的结果进行了比较。

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