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经皮清创治疗复杂性化脓性肝脓肿

Percutaneous debridement of complex pyogenic liver abscesses.

作者信息

Morettin L B, Zhan X X

机构信息

Department of Radiology, University of Texas Medical Branch, Galveston 77550.

出版信息

Chin Med J (Engl). 1992 Nov;105(11):934-9.

PMID:1304464
Abstract

The author's approach and technique in the treatment of complex liver abscesses that persisted or recurred following percutaneous drainage are described. Six patients were treated by percutaneous debridement using an instrument specially designed for that purpose. Four patients were chronically ill but stable, while the other two were septic, hypotensive and considered to be life threatened. All patients had primary pyogenic abscesses. Four had demonstrated mixed bacterial flora consisting of E. coli, Klebsiella, Proteus and gram-positive cocci and two were caused by E. coli only. Contrast enhanced CT of the abdomen in all cases revealed multiloculated or septated abscesses containing large central debris and peripheral shell or halo of compromised hepatic parenchyma. Debridement was successful in all cases, resulting in complete healing within 12 days. Follow-up for 1-4.5 years revealed no recurrences. Three cases of infected tumors of the liver were referred for treatment. CT findings in these cases demonstrated a well developed external capsule and internal septations, and the absence of a surrounding halo of compromised parenchyma distinguishes them from primary abscesses. This preliminary experience makes the authors to conclude that percutaneous debridement of pyogenic liver abscesses is a safe and curative procedure in selected cases of life-threatening chronic liver abscesses.

摘要

本文描述了作者对经皮引流后持续存在或复发的复杂肝脓肿的治疗方法和技术。6例患者采用专门为此设计的器械进行经皮清创治疗。4例患者病情慢性但稳定,另外2例患者有败血症、低血压,被认为有生命危险。所有患者均为原发性化脓性脓肿。4例显示混合菌群,包括大肠杆菌、克雷伯菌、变形杆菌和革兰氏阳性球菌,2例仅由大肠杆菌引起。所有病例的腹部增强CT显示多房或分隔的脓肿,中央有大量坏死物,周围有受损肝实质的包膜或晕环。所有病例清创均成功,12天内完全愈合。随访1至4.5年无复发。3例肝感染性肿瘤患者转诊接受治疗。这些病例的CT表现为包膜和内部间隔发育良好,无周围受损实质的晕环,这使其与原发性脓肿相区别。这一初步经验使作者得出结论,对于某些危及生命的慢性肝脓肿,经皮清创治疗是一种安全有效的方法。

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