Sandyk R, Anninos P A
Democrition University of Thrace, Department of Medical Physics, Alexandroupolis, Greece.
Int J Neurosci. 1992 Sep;66(1-2):75-85. doi: 10.3109/00207459208999791.
We have previously demonstrated that magnetoencephalographic (MEG) brain measurements in patients with seizure disorders show significant MEG activity often in the absence of conventional EEG abnormalities. We localized foci of seizure activity using the mapping technique characterized by the ISO-Spectral Amplitude (ISO-SA) on the scalp distribution of specified spectral components or frequency bands of the emitted MEG Fourier power spectrum. In addition, using an electronic device, we utilized the above recorded activity to emit back the same intensity and frequency of magnetic field to the presumed epileptic foci. Using this method we were able, over the past two and one-half years, successfully to attenuate seizure activity in a cohort of over 150 patients with various forms of epilepsy. We present a patient with severe epilepsy and behavioral disturbances in whom application of an external artificial magnetic field of low intensity produced a substantial attenuation of seizure frequency which coincided with an improvement in the patient's behavior. This case demonstrates that artificial magnetic treatment may be a valuable adjunctive procedure in the management of epilepsy.
我们之前已经证明，癫痫患者的脑磁图（MEG）测量显示，在没有传统脑电图异常的情况下，MEG活动通常很显著。我们使用以等谱振幅（ISO-SA）为特征的映射技术，在发出的MEG傅里叶功率谱的特定频谱成分或频段的头皮分布上定位癫痫活动灶。此外，我们使用电子设备，利用上述记录的活动，将相同强度和频率的磁场发射回假定的癫痫病灶。在过去两年半的时间里，通过这种方法，我们成功地减轻了150多名患有各种形式癫痫的患者的癫痫活动。我们介绍一位患有严重癫痫和行为障碍的患者，在该患者中，施加低强度的外部人工磁场可使癫痫发作频率大幅降低，同时患者的行为也有所改善。该病例表明，人工磁疗可能是癫痫治疗中一种有价值的辅助手段。
