Anninos P A, Vartzopoulos I, Razis N, Anogianakis G
Department of Neurology and Medical Physics, Medical School University of Thraki, Alexandropoulis, Greece.
Int J Neurosci. 1989 Apr;45(3-4):283-9. doi: 10.3109/00207458908986242.
Studies of the magnetoencephalogram (MEG) in epileptic patients suffering from focal epilepsies showed that activities in the MEG appear which are detectable in the scalp-recorded electroencephalogram. A novel technique was developed (Anninos et al., 1987) characterized by mapping the scalp distribution of the amplitude of the spectral components (or specific bands) of the MEG and which was termed "ISO-Spectral-Amplitude (ISO-SA) mapping." The most important findings in the 19 patients we studied from these maps were that in the frequency domain 2-7 HZ the major concentrated activity were projected on the scalp of the epileptic focus. Thus with the above noninvasive method we believe that it is possible to determine the localization of epileptiform foci via a method which will be a very useful tool for clinicians.
对患有局灶性癫痫的癫痫患者进行的脑磁图（MEG）研究表明，MEG中出现的活动在头皮记录的脑电图中是可检测到的。一种新技术被开发出来（安妮诺斯等人，1987年），其特点是绘制MEG频谱成分（或特定频段）幅度的头皮分布，该技术被称为“等谱幅度（ISO-SA）映射”。我们从这些图谱中研究的19名患者中最重要的发现是，在2 - 7赫兹的频域中，主要集中活动投射在癫痫病灶的头皮上。因此，通过上述非侵入性方法，我们相信有可能通过一种对临床医生非常有用的工具来确定癫痫样病灶的定位。
