Meador K J, Loring D W, Gallagher B B, King D W, Murro A M, Thompson E E, Lee G P, Flanigin H F, Smith J R, Dushku J
Department of Neurology, Medical College of Georgia, Augusta 30912-3200.
Int J Neurosci. 1992 Sep;66(1-2):87-91. doi: 10.3109/00207459208999792.
Hippocampal evoked potentials were recorded using the P3 tonal oddball paradigm in 30 patients with unilateral temporal lobe seizure focus. Spectral power of the evoked potentials was decreased on the side of seizure focus, but this reduction was much greater when the focus was on the left. The effect of left/right focus does not appear to be due to group differences in age, sex, seizure duration, or operative pathology. Remote or finer left/right structural differences or differential left/right hippocampal processing for the sequential tonal task are possible explanations.
在30例单侧颞叶癫痫病灶患者中，采用P3音调异常刺激范式记录海马诱发电位。癫痫病灶侧诱发电位的频谱功率降低，但当病灶在左侧时，这种降低更为明显。左右侧病灶的影响似乎并非由于年龄、性别、癫痫发作持续时间或手术病理的组间差异所致。可能的解释是存在远距离或更细微的左右结构差异，或者在顺序音调任务中左右海马处理方式不同。
