Ghigliotti G, Nigro A, Gambini C, Farris A, Burroni A, de Marchi R
Division de Dermatologie, Hôpital S. Martino, Gênes, Italie.
Ann Dermatol Venereol. 1992;119(12):968-70.
A 24-year old male patient developed, on both legs, lesions typical of Mibelli's porokeratosis 22 months after bone marrow transplantation, under treatment with cyclosporin A. He denied any family history. Mibelli's porokeratosis seldom develops after an immunosuppressive treatment, and to our knowledge it has exceptionally been described after bone marrow transplantation. A possible complication of Mibelli's porokeratosis is the development of Bowen's disease, basal or squamous cell carcinomas. Immunosuppressive treatment might facilitate the degeneration. For this reason, these subjects should be periodically and carefully examined.
一名24岁男性患者在接受骨髓移植22个月后,双腿出现典型的米贝利汗孔角化症皮损,当时正在接受环孢素A治疗。他否认有任何家族病史。米贝利汗孔角化症很少在免疫抑制治疗后发生,据我们所知,骨髓移植后发生这种病的情况极为罕见。米贝利汗孔角化症的一个可能并发症是鲍恩病、基底细胞癌或鳞状细胞癌的发生。免疫抑制治疗可能会促使其恶化。因此,应对这些患者进行定期仔细检查。