骨髓增生异常综合征患者骨髓移植后发生的非典型汗孔角化症。
Atypical porokeratosis developing following bone marrow transplantation in a patient with myelodysplastic syndrome.
作者信息
Cha Sang Hee, Park Hyun Jeong, Lee Jun Young, Cho Baik Kee
机构信息
Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
出版信息
Ann Dermatol. 2010 May;22(2):206-8. doi: 10.5021/ad.2010.22.2.206. Epub 2010 May 18.
Abstract
Porokeratosis is an abnormal disease of keratinization of epidermis. It is clinically characterized by margins covered with keratin layer and it typically has an atrophied macule with a protruded, circular form. Histopathologically, it shows the findings of cornoid lamella. Risk factors for its development include organ transplantation, long-term use of corticosteroids, immunocompromised status, including AIDS, and exposure to ultraviolet light. We herein report a case of atypical porokeratosis in a 38-year-old man who developed porokeratosis involving multiple sites following bone marrow transplantation for myelodysplastic syndrome.
摘要
汗孔角化症是一种表皮角化异常疾病。其临床特征为边缘覆盖有角质层，通常表现为萎缩性斑疹，呈突出的圆形。组织病理学上，可见鸡眼样板层的表现。其发病的危险因素包括器官移植、长期使用皮质类固醇、免疫功能低下状态（包括艾滋病）以及紫外线照射。我们在此报告一例38岁男性的非典型汗孔角化症病例，该患者在接受骨髓移植治疗骨髓增生异常综合征后出现了累及多个部位的汗孔角化症。
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