Pontone P, Crescenzi A, el Osta K, Petruzziello L, Petruzziello F, de Anna L, La Torre F
III Patologia Speciale Chirurgica, Università degli Studi La Sapienza, Roma.
Ann Ital Chir. 1992 Nov-Dec;63(6):807-10; discussion 810-1.
Prognosis for patients with malignant peritoneal mesothelioma is very poor, and most patients are beyond cure by the time the diagnosis has been made. The pathogenesis of this uncommon neoplasm seems to be related to asbestos and radiation exposure. The authors report a case of diffuse peritoneal mesothelioma in a 33-year-old man. Since the patient complained of aspecific symptoms and both biochemical and "imaging" studies did not provide useful informations for a definitive diagnosis, an exploratory laparotomy was performed. Intraoperative histological findings demonstrated the presence of a malignant peritoneal mesothelioma which had spread all over the omentum; considering the inoperability assessment of this case, the operation was completed and the patient was dismissed with an adjuvant chemo-therapy. Five weeks later the patient died.
恶性腹膜间皮瘤患者的预后非常差，大多数患者在确诊时已无法治愈。这种罕见肿瘤的发病机制似乎与接触石棉和辐射有关。作者报告了一例33岁男性的弥漫性腹膜间皮瘤病例。由于患者主诉非特异性症状，生化和“影像学”检查均未提供有助于明确诊断的信息，因此进行了剖腹探查术。术中组织学检查发现存在恶性腹膜间皮瘤，已扩散至整个大网膜；考虑到该病例无法手术切除，手术结束，患者出院并接受辅助化疗。五周后患者死亡。
