Krasomski G, Broniarczyk D, Gładysiak A
Kliniki Patologii Ciazy WAM Szpitala Połozniczo-Ginekologicznego Centrum Zdrowia Matki Polki, Lekarz Naczelny Szpitala i Kierownik.
Ginekol Pol. 1992 Sep;63(9):489-91.
An extremely rare case of melanoma amelanoticum coexisting with pregnancy has been discussed. Pregnant A. Ch., age 42, was admitted to the Polish Mother's Health Centre Memorial Hospital on the 22nd of August, 1990 with a diagnosis of the 5th pregnancy, the 2nd delivery, the 30th week of gestation, state after cesarean section. Suspected malignant melanoma. Stomach ulceration. Thrombophlebitis of left lower extremity. General condition--medium hard. For the last three days she did not report fetal movements, fetal heartbeat was not detected either. Us examination confirmed fetal death. On the 24th of August, 1990, spontaneous vaginal delivery terminated the pregnancy, giving a dead, macerated female fetus, body weight of 1500 g. On the 3rd day after delivery the patient died with growing circulation-respiratory insufficiency. Autopsy revealed melanoma malignum amelanoticum disseminatum. Neither an autopsy of the fetus nor histopathological examinations of the secundines were performed for the advanced maceration. The coexistence of pregnancy with malignant melanoma in this case brought a tragic end both for the mother and the fetus.
本文讨论了一例极其罕见的无色素性黑素瘤合并妊娠的病例。孕妇A.Ch.，42岁，于1990年8月22日入住波兰母亲健康中心纪念医院，诊断为第5次妊娠、第2次分娩、妊娠30周、剖宫产术后状态。疑似恶性黑素瘤。胃溃疡。左下肢血栓性静脉炎。一般状况——中等严重。近三天她未感觉到胎动，也未检测到胎心。超声检查证实胎儿死亡。1990年8月24日，自然阴道分娩终止妊娠，产出一死胎、浸软的女婴，体重1500克。产后第3天，患者因进行性循环呼吸功能不全死亡。尸检发现播散性无色素性恶性黑素瘤。由于胎儿高度浸软，未对胎儿进行尸检，也未对附属物进行组织病理学检查。该病例中妊娠与恶性黑素瘤并存，给母亲和胎儿都带来了悲惨的结局。
