Brigden M L
Island Medical Laboratories, Victoria, British Columbia, Canada.
West J Med. 1992 Oct;157(4):440-3.
Despite an extensive medical literature over the past ten years, patients continue to die needlessly of overwhelming postsplenectomy infection. Although physicians have become increasingly cognizant of this syndrome in children, many remain unaware of the risk to asplenic or hyposplenic adults with no underlying medical problems. In addition, many older asplenic or functionally hyposplenic persons are unaware that they are at risk for this syndrome. The identification of Howell-Jolly bodies on a peripheral blood smear should alert physicians to the need for further follow-up to establish hyposplenism and to consider possible antipneumococcal vaccination.
尽管在过去十年中有大量的医学文献,但患者仍因脾切除术后严重感染而不必要地死亡。虽然医生们越来越意识到儿童中的这种综合征,但许多人仍然没有意识到无潜在医疗问题的无脾或脾功能减退成年人面临的风险。此外,许多年龄较大的无脾或功能脾功能减退的人并不知道自己有患这种综合征的风险。在外周血涂片上发现豪-焦小体应提醒医生需要进一步随访以确定脾功能减退,并考虑可能的抗肺炎球菌疫苗接种。