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动脉平滑肌中横桥的ATP利用

Cross bridge ATP utilization in arterial smooth muscle.

作者信息

Paul R J, Glück E, Rüegg J C

出版信息

Pflugers Arch. 1976 Feb 24;361(3):297-9. doi: 10.1007/BF00587295.

DOI:10.1007/BF00587295
PMID:130614
Abstract

Measurements of oxygen consumption and lactate production were used to estimate the ATP production in porcine carotid arteries. Changes in the total energy metabolism were correlated with changes in force which was altered by changing the muscle length under maximum stimulation. This tension-dependent metabolism could be used to distinguish between cross bridge and other ATP utilization. The tension-dependent metabolism was equal under K+ -depolarization or histamine stimulation. Tension cost was 300x smaller than skeletal muscle while the cross bridge cycle duration 30x longer.

摘要

通过测量氧消耗量和乳酸生成量来估算猪颈动脉中的ATP生成量。总能量代谢的变化与力的变化相关，而力的变化是通过在最大刺激下改变肌肉长度来实现的。这种张力依赖性代谢可用于区分横桥和其他ATP利用情况。在K⁺去极化或组胺刺激下，张力依赖性代谢是相同的。张力消耗比骨骼肌小300倍，而横桥循环持续时间长30倍。

相似文献

1
Cross bridge ATP utilization in arterial smooth muscle.动脉平滑肌中横桥的ATP利用
Pflugers Arch. 1976 Feb 24;361(3):297-9. doi: 10.1007/BF00587295.
2
The aerobic metabolism of porcine carotid artery and its relationship to isometric force. Energy cost of isometric contraction.
Pflugers Arch. 1977 Jul 29;370(1):9-18. doi: 10.1007/BF00707939.
3
High K+,Na+-deficient solution inhibits tension, O2 consumption, and ATP synthesis in smooth muscle.高钾、低钠溶液可抑制平滑肌的张力、耗氧量和ATP合成。
Jpn J Pharmacol. 1982 Aug;32(4):727-33. doi: 10.1254/jjp.32.727.
4
Oxygen consumption and lactate production of the rat portal vein in relation to its contractile activity.大鼠门静脉的氧消耗和乳酸生成与其收缩活动的关系。
Acta Physiol Scand. 1977 May;100(1):91-106. doi: 10.1111/j.1748-1716.1977.tb05925.x.
5
Comments on: oxygen tension sensors in vascular smooth muscle.
Adv Exp Med Biol. 1977;78:117-22. doi: 10.1007/978-1-4615-9035-4_8.
6
Effect of histamine on the energy metabolism of K+-depolarized hog carotid artery.组胺对钾离子去极化猪颈动脉能量代谢的影响。
Circ Res. 1982 Jun;50(6):848-55. doi: 10.1161/01.res.50.6.848.
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Energetic cost of activation processes during contraction of swine arterial smooth muscle.猪动脉平滑肌收缩过程中激活过程的能量消耗。
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[Temperature and activity of the smooth muscle--with special reference to effects of temperature on contraction and ion transfer].[平滑肌的温度与活性——特别提及温度对收缩和离子转运的影响]
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本文引用的文献

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Energy cost of tonic contraction in a lamellibranch catch muscle.瓣鳃纲动物抓握肌强直收缩的能量消耗
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Characterization of cross-bridge elasticity and kinetics of cross-bridge cycling during force development in single smooth muscle cells.单个平滑肌细胞在力产生过程中横桥弹性及横桥循环动力学的表征。
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Smooth muscle myosin cross-bridge interactions modulate actin filament sliding velocity in vitro.平滑肌肌球蛋白横桥相互作用在体外调节肌动蛋白丝滑动速度。
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Adenosine 5'-triphosphate consumption by smooth muscle as predicted by the coupled four-state crossbridge model.由耦合四态横桥模型预测的平滑肌对三磷酸腺苷的消耗。
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Pflugers Arch. 1977 Jul 29;370(1):9-18. doi: 10.1007/BF00707939.
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Length-tension relationship of smooth muscle of the hog carotid artery.猪颈动脉平滑肌的长度-张力关系。
Circ Res. 1973 Sep;33(3):275-83. doi: 10.1161/01.res.33.3.275.
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The effect of the performance of work on total energy output and metabolism during muscular contraction.肌肉收缩过程中工作表现对总能量输出和新陈代谢的影响。
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Apparent P-O ratio and chemical energy balance in frog sartorius muscle in vitro.体外青蛙缝匠肌中的表观磷氧比与化学能量平衡
Biochim Biophys Acta. 1974 Jun 28;347(3):483-90. doi: 10.1016/0005-2728(74)90085-1.
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A nonequilibrium thermodynamic description of vascular smooth muscle mechanochemistry. I. The rate of oxygen consumption: a measure of the driving chemical reaction.血管平滑肌机械化学的非平衡热力学描述。I. 耗氧率：驱动化学反应的一种度量
J Mechanochem Cell Motil. 1974;3(1):19-32.
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Aerobic glycolysis in vascular smooth muscle: relation to isometric tension.
Biochim Biophys Acta. 1974 Aug 23;357(2):167-76. doi: 10.1016/0005-2728(74)90057-7.
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Influences of calcium concentration and pH on the tension development and ATPase activity of the arterial actomyosin contractile system.钙浓度和pH值对动脉肌动球蛋白收缩系统张力发展及ATP酶活性的影响。
Blood Vessels. 1974;11(5-6):277-86. doi: 10.1159/000158021.