Deda G, Akinci A, Teziç T, Karagöl U
Dr. Sami Ulus Children's Hospital, Ankara.
Turk J Pediatr. 1992 Oct-Dec;34(4):239-44.
Serum total and free thyroid hormones, reverse T3 (rT3), thyroxin binding globulin (TBG) and thyroid stimulating hormone (TSH) concentrations were measured in 35 epileptic patients receiving anticonvulsants (phenobarbitone, phenytoin). There was a significant reduction found in total thyroxine (TT4), free thyroxine (FT4), total triiodothyronine (TT3), free triiodothyronine (FT3) and rT3 in the group treated with, phenytoin. The thyroid hormone levels were within normal limits in the group receiving phenobarbitone.
对35名接受抗惊厥药物（苯巴比妥、苯妥英）治疗的癫痫患者测定了血清总甲状腺激素和游离甲状腺激素、反三碘甲状腺原氨酸（rT3）、甲状腺素结合球蛋白（TBG）以及促甲状腺激素（TSH）的浓度。在用苯妥英治疗的组中，总甲状腺素（TT4）、游离甲状腺素（FT4）、总三碘甲状腺原氨酸（TT3）、游离三碘甲状腺原氨酸（FT3）和rT3显著降低。接受苯巴比妥治疗的组中甲状腺激素水平在正常范围内。
