Liu Y H, Wang X G, Chen Y T
Institute of Infectious and Parasitic Diseases, Chongqing University ofMedical Sciences.
Zhonghua Nei Ke Za Zhi. 1992 Dec;31(12):761-3, 780.
Fifteen cases of alveolar echinococcosis were treated with albendazole in a dosage of 20 mg/kg/d x 30 days for 12-60 courses (25.8 courses in average) and were followed up 1-7 years (48 months in average) with computerized tomography and ultrasonography. Abdominal pain in all the cases, jaundice in 4 and hemoptysis in disappeared 2. In 13 of the 15 cases, the hepatic lesions reduced in size. Among 9 cases examined with computerized tomography, the hepatic lesions were completely calcified in 5 and enclosed with calcified walls in 3. Only one patient with huge and extensive hepatic lesions showed no apparent improvement. No severe adverse reaction was observed. Evidently albendazole was effective in the treatment of alveolar echinococcosis.
15例肺泡型棘球蚴病患者接受阿苯达唑治疗，剂量为20mg/kg/d，共30天，疗程为12 - 60个疗程（平均25.8个疗程），并通过计算机断层扫描和超声检查进行了1 - 7年（平均48个月）的随访。所有病例均有腹痛，4例出现黄疸，2例咯血症状消失。15例中的13例肝脏病变体积缩小。在9例接受计算机断层扫描检查的病例中，5例肝脏病变完全钙化，3例被钙化壁包绕。只有1例肝脏病变巨大且广泛的患者未见明显改善。未观察到严重不良反应。显然，阿苯达唑对肺泡型棘球蚴病的治疗有效。
