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接受阿苯达唑治疗的肺泡型肝包虫病患者的肝脏计算机断层扫描

Computer tomography of liver in alveolar echinococcosis treated with albendazole.

作者信息

Liu Y H, Wang X G, Chen Y T, Yao Y Q

机构信息

Institute of Parasitic Diseases, Chongqing University of Medical Sciences, Sichuan, People's Republic of China.

出版信息

Trans R Soc Trop Med Hyg. 1993 May-Jun;87(3):319-21. doi: 10.1016/0035-9203(93)90147-i.

DOI:10.1016/0035-9203(93)90147-i
PMID:8236407
Abstract

Fourteen cases of alveolar echinococcosis were examined by computed tomographic (CT) scanning of the liver, including 3 cases before treatment and 11 cases 2.0-7.5 years after long-term continuous albendazole therapy. In 7 cases the hepatic lesions were almost completely calcified and cured, while in 3 cases incomplete calcification of the peripheral margin of the hepatic lesions was observed. CT scanning of the one uncured case and the 3 cases before treatment showed active lesions with heterogeneous hypodense areas in the liver without calcification on the peripheral margin. Long-term continuous albendazole therapy can result in parasitological cure with death of the parasite.

摘要

对14例肺泡型包虫病患者进行了肝脏计算机断层扫描(CT)检查,其中3例为治疗前患者,11例为长期连续使用阿苯达唑治疗2.0至7.5年后的患者。7例患者肝脏病变几乎完全钙化并治愈,3例患者肝脏病变周边边缘出现不完全钙化。对1例未治愈病例和3例治疗前病例的CT扫描显示,肝脏有活动性病变,呈不均匀低密度区,周边边缘无钙化。长期连续使用阿苯达唑治疗可导致寄生虫死亡从而实现寄生虫学治愈。

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1
Computer tomography of liver in alveolar echinococcosis treated with albendazole.接受阿苯达唑治疗的肺泡型肝包虫病患者的肝脏计算机断层扫描
Trans R Soc Trop Med Hyg. 1993 May-Jun;87(3):319-21. doi: 10.1016/0035-9203(93)90147-i.
2
[Computerized tomography of liver in alveolar echinococcosis treated with albendazole].
Zhonghua Nei Ke Za Zhi. 1993 Nov;32(11):733-5.
3
[Continuous albendazole therapy in alveolar echinococcosis--evaluation of therapeutic effect with computerized tomography and ultrasonography].[阿苯达唑持续治疗泡型包虫病——应用计算机断层扫描和超声检查评估治疗效果]
Zhonghua Nei Ke Za Zhi. 1992 Dec;31(12):761-3, 780.
4
Preliminary observation of continuous albendazole therapy in alveolar echinococcosis.
Chin Med J (Engl). 1991 Nov;104(11):930-3.
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Continuous albendazole therapy in alveolar echinococcosis: long-term follow-up observation of 20 cases.连续使用阿苯达唑治疗泡型包虫病:20 例长期随访观察。
Trans R Soc Trop Med Hyg. 2009 Aug;103(8):768-78. doi: 10.1016/j.trstmh.2009.04.006. Epub 2009 May 19.
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Effect of albendazole on recurrent and residual alveolar echinococcosis of the liver after surgery.
Hepatology. 1997 Mar;25(3):528-31. doi: 10.1002/hep.510250305.
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Alveolar echinococcosis - a rare disease with differential diagnostic problems.肺泡型棘球蚴病——一种存在鉴别诊断问题的罕见疾病。
Rozhl Chir. 2016 Summer;95(6):240-4.
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Continuous long-term albendazole therapy in intraabdominal cystic echinococcosis.阿苯达唑持续长期治疗腹腔囊性棘球蚴病。
Chin Med J (Engl). 2000 Sep;113(9):827-32.
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Long-term albendazole treatment in one case of alveolar echinococcosis. Case report.1例肺泡型棘球蚴病的阿苯达唑长期治疗。病例报告。
Acta Gastroenterol Belg. 2003 Jul-Sep;66(3):255-7.
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Evaluation of response to chemotherapy of human cystic echinococcosis.人体囊型包虫病化疗反应的评估
Br J Radiol. 1990 Jul;63(751):523-31. doi: 10.1259/0007-1285-63-751-523.

引用本文的文献

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Simple liver cysts and cystoid lesions in hepatic alveolar echinococcosis: a retrospective cohort study with Hounsfield analysis.单纯性肝囊肿和肝泡型包虫病的囊样病变:一项基于 Hounsfield 分析的回顾性队列研究。
Parasite. 2019;26:54. doi: 10.1051/parasite/2019057. Epub 2019 Aug 30.
2
[Chemotherapy of alveolar echinococcosis with benzimidazoles. A prospective long-term study].[苯并咪唑类药物治疗肺泡型棘球蚴病的前瞻性长期研究]
Med Klin (Munich). 1998 Aug 15;93(8):463-7. doi: 10.1007/BF03042595.
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Anthelmintics. A comparative review of their clinical pharmacology.
驱虫药。其临床药理学的比较综述。
Drugs. 1997 May;53(5):769-88. doi: 10.2165/00003495-199753050-00004.