HARMAN J W, OSBORNE U H
J Exp Med. 1953 Jul;98(1):81-98. doi: 10.1084/jem.98.1.81.
In pigeon breast muscle the mitochondria are the principal site of oxidative metabolism, whereas the myofibrils are incapable of oxidizing intermediates of the Krebs cycle. The mitochondria contain the oxidative enzymes, and the sarcosomes are associated with a factor which accelerates the mitochondrial oxidative rate. The maintenance of myofibrillar contractility and structure is closely correlated with preservation of mitochondrial oxidative capacity and structure. By use of fluoride and dinitrophenol the connection between mitochondrial metabolism and myofibrillar behavior is shown to occur through the process of oxidative phosphorylation.
在鸽胸肌中，线粒体是氧化代谢的主要场所，而肌原纤维无法氧化三羧酸循环的中间产物。线粒体含有氧化酶，肌粒与一种能加速线粒体氧化速率的因子相关。肌原纤维收缩性和结构的维持与线粒体氧化能力和结构的保存密切相关。通过使用氟化物和二硝基苯酚，线粒体代谢与肌原纤维行为之间的联系被证明是通过氧化磷酸化过程发生的。
