Marumo K, Nagaki T, Nakamura Y
Department of Clinical Pathology, Showa University Fujigaoka Hospital, Yokohama.
Rinsho Byori. 1992 Dec;40(12):1312-8.
O-serotypes, biotypes, and drug resistance of Serratia marcescens strains isolated from various clinical specimens in Showa University Fujigaoka Hospital were investigated: period I (1979. 1-1982.3), 122 strains; period II (1983. 1-1985. 3), 198; period III (1985. 4-198. 3), 129; period IV (1989. 1-1991. 3), 99. The frequency of serotype O 3 was higher than those of the other serotypes after the period II and ranged 17 to 37%. The isolation frequency (27%) of serotype O 4 was higher than those of other serotypes in the period I. However, this frequency decreased in the period II to III and, in the period IV (10%), was higher than in the period III. The isolation frequency of serotype O 17 suddenly increased in the period II (27%) alone, and 42% of the biotypes, obtained with API 20E, showed 5305701. The isolation frequency of non-typable strains ranged 9 to 14% through all periods. The group including 5317721 and 5307721 clustered by the furthest neighbor method, more frequently appeared through all periods. The former code of urease positive more frequently appeared in the period II to IV. The isolation frequency of the latter code of urease negative reduced to a minimum (18%) in period II, though it increased in the period II to IV. The isolation frequency (22%) of the pigmented strains in the period IV increased much higher than in the period I to III (ranged 2 to 4%). The frequency of the pigmented strains of serotype O 3, not belonged to the Grimont's biotype, was 27% of all pigmented strains isolated in the period IV.(ABSTRACT TRUNCATED AT 250 WORDS)
对昭和大学藤冈医院从各种临床标本中分离出的粘质沙雷氏菌菌株的O血清型、生物型和耐药性进行了调查：第一阶段（1979年1月 - 1982年3月），122株；第二阶段（1983年1月 - 1985年3月），198株；第三阶段（1985年4月 - 1988年3月），129株；第四阶段（1989年1月 - 1991年3月），99株。第二阶段之后，O3血清型的频率高于其他血清型，范围在17%至37%。O4血清型的分离频率在第一阶段（27%）高于其他血清型。然而，该频率在第二阶段至第三阶段下降，在第四阶段（10%）高于第三阶段。O17血清型的分离频率仅在第二阶段突然增加（27%），并且用API 20E获得的生物型中有42%显示为5305701。不可分型菌株的分离频率在所有阶段范围为9%至14%。包括5317721和5307721的组通过最远邻法聚类，在所有阶段更频繁出现。脲酶阳性的前一个编码在第二阶段至第四阶段更频繁出现。脲酶阴性的后一个编码的分离频率在第二阶段降至最低（18%），尽管在第二阶段至第四阶段有所增加。第四阶段有色菌株的分离频率（22%）比第一阶段至第三阶段（范围为2%至4%）大幅增加。不属于格里蒙生物型的O3血清型有色菌株的频率在第四阶段分离的所有有色菌株中为27%。
