Pinheiro M C, Beraldo P S, Junqueira Júnior L F, Lopes E R, Chapadeiro E
Faculdade de Medicina do Triângulo Mineiro, Uberaba, MG.
Rev Soc Bras Med Trop. 1992 Jan-Mar;25(1):45-50. doi: 10.1590/s0037-86821992000100007.
We did mast cell and eosinophil granulocyte counts in the myocardium of forty chronic chagasic Wistar albino rats. We used 10 controls rats and 30 animals with late-stage (8th month) infection of São Felipe, Y and Colombian Trypanosoma cruzi strains, with variable degree of chronic myocarditis. We found chronic fibrosing myocarditis (fibrosis) in 40% of the infected animals. It was detected increased mast cell count in the chagasic rats associated with infection and not related with myocardial fibrosis. There was no increase in the eosinophil counts.
我们对40只患有慢性恰加斯病的Wistar白化大鼠的心肌进行了肥大细胞和嗜酸性粒细胞计数。我们使用了10只对照大鼠和30只感染了圣费利佩Y株和哥伦比亚克氏锥虫株的晚期（第8个月）动物，这些动物患有不同程度的慢性心肌炎。我们发现40%的受感染动物患有慢性纤维性心肌炎（纤维化）。在患有恰加斯病的大鼠中，检测到与感染相关而非与心肌纤维化相关的肥大细胞计数增加。嗜酸性粒细胞计数没有增加。
