Michie D D, Cowan D F, Cain C P, Bell C C
Ann Surg. 1976 Mar;183(3):307-13. doi: 10.1097/00000658-197603000-00017.
Thirteen femoral vein autografts were placed into the corresponding ipsilateral femoral arteries of 8 mongrel dogs. Cuff-type Doppler (ultrasonic) flowmeters were placed around six of the grafts. None of the vessels thrombosed. Blood flow velocities were measured in all vessels up until the time of sacrifice (mean 95 +/- 5 days after surgery) or accidental death (one dog, 49 days after surgery). The only case of graft failure was attributed to infection at the flowmeter site. With this single exception, the vein grafts exhibited uniformity in histological appearance from dog to dog. These data suggest that implantation of properly designed Doppler flow transducers may have clinical applications. This technique permits continuous or intermittent assessment of blood flow characteristics through a graft without additional trauma or cost to the patient. It is free of the many inherent disadvantages of chronically implanted electromagnetic flowmeters and may negate the need in some instances for followup angiographic studies.
将13条股静脉自体移植物植入8只杂种狗的同侧相应股动脉中。在6条移植物周围放置了袖带式多普勒（超声）流量计。所有血管均未发生血栓形成。在处死动物（术后平均95±5天）或意外死亡（1只狗，术后49天）之前，测量了所有血管的血流速度。唯一的移植物失败病例归因于流量计部位的感染。除了这一例外情况，不同狗之间的静脉移植物在组织学外观上表现出一致性。这些数据表明，植入设计合理的多普勒流量传感器可能具有临床应用价值。该技术允许在不增加患者额外创伤或费用的情况下，连续或间歇性地评估通过移植物的血流特征。它没有长期植入的电磁流量计的许多固有缺点，并且在某些情况下可能无需进行后续血管造影研究。
