Deleanu M, Prelipceanu O
Morphol Embryol (Bucur). 1975;21(4):273-5.
Macrophage transformation of the fibroblasts and the attraction of macrophages in cell cultures of chick embryo have been investigated. Cultures were treated with choline hydrochloride, DNA, lactalbumine hydrolysate, lysine, peptone and ATP. An intense agglomeration of macrophages in the contact area with the agar gel containing choline could be observed. Cultures treated with DNA have a great number of macrophages together with a numerous fibroblast population. In cultures treated with the other substances, macrophages also appear, yet their number is not so great. The results obtained plead for a triggering of the macrophage reaction and of the necrosis in embryo tissues and organs by substances identical or similar to those used in our cultures.
已对鸡胚细胞培养物中纤维母细胞的巨噬细胞转化以及巨噬细胞的吸引作用进行了研究。培养物用盐酸胆碱、DNA、乳白蛋白水解物、赖氨酸、蛋白胨和三磷酸腺苷处理。在与含胆碱的琼脂凝胶接触区域可观察到巨噬细胞强烈聚集。用DNA处理的培养物中有大量巨噬细胞以及众多的纤维母细胞群体。在用其他物质处理的培养物中也出现了巨噬细胞，但其数量没有那么多。所获结果表明，我们培养物中使用的相同或相似物质可引发胚胎组织和器官中的巨噬细胞反应和坏死。
