Maehara Y, Sakaguchi Y, Moriguchi S, Orita H, Korenaga D, Kohnoe S, Sugimachi K
Department of Surgery II, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Cancer. 1992 Apr 1;69(7):1645-50. doi: 10.1002/1097-0142(19920401)69:7<1645::aid-cncr2820690702>3.0.co;2-x.
Between 1965 and 1985, 51 of 1500 patients (3.4%) with gastric cancer who had gastric resection had signet ring cell gastric cancer. Patients with this form of cancer tended to be younger and female; the tumors were smaller and involved the stomach body, serosal invasion was less prominent, and lymph node metastases were less likely to be present. Early mucosal and submucosal cancer was present in 54.9% of the patients with the signet ring cell and in 24.6% with other types of gastric cancer. In 15.7% of patients with signet ring cell cancer, a noncurative resection was performed. The 5-year survival rate was 74.5% for patients with signet ring cell cancer and 52.4% for those with other types of gastric cancer (P less than 0.01). In patients with signet ring cell gastric cancer, the lesion is less extensive; thus, these patients probably can expect a longer survival time.
1965年至1985年间，1500例接受胃癌胃切除术的患者中有51例（3.4%）为印戒细胞型胃癌。这种癌症患者往往更年轻且多为女性；肿瘤较小，累及胃体，浆膜侵犯不那么明显，且较少出现淋巴结转移。印戒细胞型胃癌患者中54.9%存在早期黏膜和黏膜下癌，其他类型胃癌患者中这一比例为24.6%。15.7%的印戒细胞癌患者进行了非根治性切除。印戒细胞癌患者的5年生存率为74.5%，其他类型胃癌患者为52.4%（P<0.01）。在印戒细胞型胃癌患者中，病变范围较小；因此，这些患者可能预期生存时间更长。
