胃印戒细胞癌的特征
Characterization of signet ring cell carcinoma of the stomach.
作者信息
Otsuji E, Yamaguchi T, Sawai K, Takahashi T
机构信息
First Department of Surgery, Kyoto Prefectural University of Medicine, Japan.
出版信息
J Surg Oncol. 1998 Apr;67(4):216-20. doi: 10.1002/(sici)1096-9098(199804)67:4<216::aid-jso2>3.0.co;2-b.
BACKGROUND AND OBJECTIVES
As there is no consensus regarding the prognosis of patients with signet cell carcinoma of the stomach compared with other types of gastric cancer, we retrospectively studied the clinicopathologic features and prognosis of signet cell carcinoma in comparison with other types of gastric cancer.
METHODS
Gastrectomies were performed because of gastric cancer in 1,498 patients between 1970 and 1994. Of the 154 patients diagnosed with signet ring cell carcinoma, 94 had early and 60 had advanced gastric carcinoma. The percentage of patients with an early carcinoma was significantly higher among those with signet ring cell carcinoma compared with those with other gastric carcinoma histologies.
RESULTS
The survival of the total group of patients with signet ring cell carcinoma was significantly better than that of patients with other types of gastric carcinoma (P < 0.05). Survival of the subset of patients with early signet ring cell carcinoma was also improved compared with patients with other types of gastric carcinoma (P < 0.05). However, patients with advanced signet ring cell carcinoma had a poor prognosis similar to that of patients with other types of gastric carcinoma.
背景与目的
由于胃印戒细胞癌患者与其他类型胃癌患者的预后尚无共识，我们回顾性研究了胃印戒细胞癌与其他类型胃癌相比的临床病理特征及预后。
方法
1970年至1994年间，1498例因胃癌接受胃切除术。在154例诊断为印戒细胞癌的患者中，94例为早期胃癌，60例为进展期胃癌。与其他组织学类型的胃癌患者相比，印戒细胞癌患者中早期癌患者的比例显著更高。
结果
胃印戒细胞癌患者总体生存率显著优于其他类型胃癌患者（P < 0.05）。早期胃印戒细胞癌患者亚组的生存率也高于其他类型胃癌患者（P < 0.05）。然而，进展期胃印戒细胞癌患者的预后与其他类型胃癌患者相似较差。
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