Dvorák M, Raszyk J
Physiol Bohemoslov. 1976;25(1):7-11.
Suckling piglets aged 28-31 days and weaned piglets aged 46-60 days were injected with insulin at a rate of 1 U/kg body weight to induce hypoglycaemia. All the animals were blood-sampled before and 45 and 90 minutes after the insulin injection. Both groups developed a marked adrenocortical response without any significant differences, though the rise in plasma 17-hydroxycorticosteroid (17-OHCS) levels of weaned piglets was slightly delayed. Plasma vitamin E concentration showed a significant rise in suckling piglets and a slight rise in weaned animals; it was not accompanied by an increase in total cholesterol levels. The results suggest that glucocorticoids affect vitamin E metabolism. The values of plasma 17-OHCS, cholesterol and vitamin E levels as well as of blood glucose levels and circulating eosinophil leucocyte counts confirmed differences in these parameters between suckling and weaned piglets.
对28 - 31日龄的哺乳仔猪和46 - 60日龄的断奶仔猪按1单位/千克体重的剂量注射胰岛素以诱导低血糖。所有动物在胰岛素注射前、注射后45分钟和90分钟采集血样。两组均出现明显的肾上腺皮质反应，且无显著差异，不过断奶仔猪血浆17 - 羟皮质类固醇（17 - OHCS）水平的升高略有延迟。血浆维生素E浓度在哺乳仔猪中显著升高，在断奶仔猪中略有升高；且总胆固醇水平未随之升高。结果表明糖皮质激素影响维生素E代谢。血浆17 - OHCS、胆固醇和维生素E水平以及血糖水平和循环嗜酸性粒细胞计数的值证实了哺乳仔猪和断奶仔猪在这些参数上存在差异。
