Neville H E, Baumbach L L, Ringel S P, Russo L S, Sujansky E, Garcia C A
Department of Neurology, University of Colorado School of Medicine, Denver.
Neurology. 1992 Apr;42(4):897-902. doi: 10.1212/wnl.42.4.897.
We report a kindred manifesting clinical features and muscle biopsy findings of inclusion body myositis (IBM). In this family, multiple members were affected in two generations with direct male-to-male and female-to-male transmission. This is the first reported instance of autosomal dominant inheritance in IBM, which usually occurs sporadically or, rarely, may be transmitted as an autosomal recessive disorder.
我们报告了一个具有包涵体肌炎（IBM）临床特征和肌肉活检结果的家族。在这个家族中，两代人中多个成员患病，存在男性到男性以及女性到男性的直接遗传。这是首次报道的IBM常染色体显性遗传病例，IBM通常为散发性，或极少情况下可能以常染色体隐性疾病形式遗传。
