Böttger T, Gabbert H, Stöckle M, Wellek S, Menke H, Jauckus H C, Grenz A, Heintz A, Junginger T
Klinik und Poliklinik für Allgemein- und Abdominalchirurgie, Johannes-Gutenberg-Universität, Mainz, BRD.
Langenbecks Arch Chir. 1992;377(1):4-8. doi: 10.1007/BF00186141.
After curative resection of stomach carcinomas (adenocarcinomas: n = 58, signet ring cell carcinomas: n = 24, undifferentiated carcinomas: n = 21) the DNA content of the tumor cells was compared with the histomorphological parameters. There was a correlation between the DNA content and the histomorphological parameters. The DNA analysis had no additionally prognostic influence. In the multivariate regression analysis the prognosis depended on lymph node status (p = 0.0009), pT-stage (p = 0.02), tumor localization (p = 0.03) and the histological type (p = 0.05). The prognosis was independent of the DNA content. Furthermore, neither did the degree of differentiation, the operative procedure, the safety distance, the size of the tumor, the sex nor the age of the patient have any influence on the prognosis.
对胃癌（腺癌：n = 58，印戒细胞癌：n = 24，未分化癌：n = 21）进行根治性切除后，将肿瘤细胞的DNA含量与组织形态学参数进行比较。DNA含量与组织形态学参数之间存在相关性。DNA分析没有额外的预后影响。在多变量回归分析中，预后取决于淋巴结状态（p = 0.0009）、pT分期（p = 0.02）、肿瘤定位（p = 0.03）和组织学类型（p = 0.05）。预后与DNA含量无关。此外，分化程度、手术方式、安全切缘、肿瘤大小、患者性别及年龄均对预后无影响。
