González Sotos M A
An Esp Pediatr. 1976 Jan-Feb;9(1):38-41.
Levels of serum alkaline phosphatase activity were determined in a sample of 110 individuals affected by Down's syndrome, and in a sample of 299 healthy persons, males and females. The age of both populations was from 6 to 28. They were located in Madrid, but hailing from several Spanish provinces. Levels are higher for all age groups than those in the control population. Differences between both populations are statistically significant in the following age groups: from 6 to 8, 11 to 13 and 14 to 16. Other studies on alkaline phosphatase in various tissues were examined and the possible significance of this finding is discussed.
对110名唐氏综合征患者以及299名年龄在6至28岁之间的健康男女样本进行了血清碱性磷酸酶活性水平测定。这些人都来自西班牙多个省份，居住在马德里。所有年龄组的血清碱性磷酸酶活性水平均高于对照组人群。在以下年龄组中，两组人群之间的差异具有统计学意义：6至8岁、11至13岁和14至16岁。本文还研究了其他关于不同组织中碱性磷酸酶的研究，并讨论了这一发现的可能意义。
