Liang L, Johnstone R M
Department of Biochemistry, McGill University, Montreal, Canada.
Biochim Biophys Acta. 1992 Apr 29;1106(1):189-96. doi: 10.1016/0005-2736(92)90238-h.
Comparisons of the site specific binding of nitrobenzylthioinosine (NBMPR) to intact and lysed red cells from various mammalian and avian species suggest the presence of a cytoplasmic pool of nucleoside transporters. In some species the cytoplasmic pool is about 50% of the total (mouse). On the average, the cytoplasmic pool is approx. 20% of the surface pool of NBMPR-binding sites. In sheep reticulocytes, both pools disappear in an energy-dependent manner during the maturation of the reticulocyte in vitro.
对硝基苄硫代肌苷（NBMPR）与来自各种哺乳动物和鸟类物种的完整红细胞及裂解红细胞的位点特异性结合进行比较，提示存在核苷转运体的细胞质池。在某些物种中，细胞质池约占总量的50%（小鼠）。平均而言，细胞质池约为NBMPR结合位点表面池的20%。在绵羊网织红细胞中，在体外网织红细胞成熟过程中，这两个池均以能量依赖的方式消失。
