Reñé R, Mascaró J, Pérez J L, Bolao F, Martínez-Matos J A, Podzamczer D
Servicio de Neurología, Enfermedades Infecciosas, Hospital de Bellvitge-Prínceps d'Espanya, Barcelona.
Med Clin (Barc). 1992 Apr 4;98(13):499-501.
The case of a HIV positive patient with lumbosacral polyradiculomyelitis by cytomegalovirus (PLS-CMV) is presented. The patient was a homosexual male receiving maintainance treatment with foscarnet for previous corioretinitis by CMV who consulted for paraparesia and sphincter disorders of a 3 week evolution. Neutrophilic pleocytosis and high levels of glucose and proteins were observed on LCR and CMV isolated discarding other entities. The LCR normalized upon treatment with gancyclovir although serious residual paraparesia persisted. PLS-CMV is an infrequent entity of typical clinic and liquoral characteristics. Recognition of the same is important since favorable response depends on early anti-CMV treatment.
本文介绍了一例因巨细胞病毒导致腰骶部多神经根脊髓炎（PLS-CMV）的HIV阳性患者。该患者为同性恋男性，此前因巨细胞病毒引起的视网膜炎接受膦甲酸钠维持治疗，此次因双下肢轻瘫和括约肌功能障碍就诊，病程3周。腰椎穿刺显示中性粒细胞增多，葡萄糖和蛋白质水平升高，分离出巨细胞病毒，排除其他病因。使用更昔洛韦治疗后腰椎穿刺结果恢复正常，但严重的双下肢轻瘫残留症状仍持续存在。PLS-CMV是一种临床和脑脊液特征均典型但不常见的疾病。认识到这一点很重要，因为良好的反应取决于早期抗巨细胞病毒治疗。
