Mahieux F, Gray F, Fenelon G, Gherardi R, Adams D, Guillard A, Poirier J
Clinique Neurologique, Hôpital Tenon, Paris, France.
J Neurol Neurosurg Psychiatry. 1989 Feb;52(2):270-4. doi: 10.1136/jnnp.52.2.270.
A 26 year old male intravenous drug abuser presented with rapidly progressive paraplegia and total incontinence. CSF examination showed elevated protein level and pleocytosis. HIV testing was positive. Anti CMV titres were mildly elevated in serum and CSF. Death occurred 26 days after the onset of neurological signs. Necrotic and inflammatory lesions with numerous inclusion bodies characteristic of CMV were found in the roots of the cauda equina, conus terminalis and lumbar segments of the spinal cord. CMV subependymal encephalitis and HIV encephalitis were also present.
一名26岁的男性静脉注射吸毒者出现快速进展的截瘫和完全失禁。脑脊液检查显示蛋白水平升高和细胞增多。HIV检测呈阳性。血清和脑脊液中抗巨细胞病毒滴度轻度升高。在神经症状出现26天后死亡。在马尾神经根、终丝和脊髓腰段发现了具有巨细胞病毒特征性大量包涵体的坏死性和炎性病变。还存在巨细胞病毒室管膜下脑炎和HIV脑炎。
