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通过心理社会刺激在动物中诱发急慢性心血管疾病。

The induction of acute and chronic cardiovascular disease in animals by psychosocial stimulation.

作者信息

Henry J P

出版信息

Int J Psychiatry Med. 1975;6(1-2):147-58. doi: 10.2190/499M-FN7J-WCL4-H873.

DOI:10.2190/499M-FN7J-WCL4-H873
PMID:131784
Abstract

It has been established that sustained emotional arousal can accompany the psychosocial stimulation induced by the social interaction of members of a social group as they compete for desiderata, such as food and water. This paper reviews the evidence that this arousal of neuronendocrine response patterns can, in turn, lead to disease states and to a fatal outcome. Various experimental observations in pigs, monkeys, baboons, tree shrews, and rodents demonstrate both acute and chronic disturbances of cardiovascular function. These conditions can lead to sudden death or to sustained high blood pressure with arteriosclerotic lesions in the heart and blood vessels. It is shown that when social pressure that has been maintained for a sufficiently long period is relieved, the organism does not revert to normal.

摘要

已经确定,当一个社会群体的成员为获取食物和水等必需品而竞争时,其社会互动所引发的心理社会刺激可能会伴随着持续的情绪唤醒。本文回顾了相关证据,即这种神经内分泌反应模式的唤醒反过来可能导致疾病状态和致命后果。在猪、猴子、狒狒、树鼩和啮齿动物身上的各种实验观察表明,心血管功能存在急性和慢性紊乱。这些情况可能导致猝死或持续的高血压,并伴有心脏和血管的动脉硬化病变。研究表明,当持续足够长时间的社会压力得到缓解时,机体并不会恢复正常。

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